Introducing NeuroGuide 4.0.1

NeuroGuide 4.0.1 is the latest version of the leading software in Quantitative EEG (QEEG) analysis and neurofeedback, developed by Applied Neuroscience, Inc. (ANI). This software is designed as a comprehensive “toolbox” for physicians, psychologists, neurologists, and researchers to link clinical symptoms to functional brain networks and provide more accurate assessments of brain function.

This software has been used with over 20,000 patients and holds digital EEG data from more than 20,000 subjects over the past 40 years. NeuroGuide is a registered FDA medical device (K041263) valid for clinical use.

Main Features of NeuroGuide 4.0.1

This software offers a wide range of analysis and neurofeedback capabilities to users, the most important of which include:

EEG Analysis & Processing

• Import from 45 Different EEG Amplifier Formats: Compatibility with various devices on the market
• Automatic Artifact Removal Without Phase Distortion: Precise cleaning of data from eye, muscle, and other interference
• Manual EEG Editing: User review and precise editing of signals
• Export to Various Formats: EDF, ASCII, Lexicor, and LORETA-compatible formats
• FFT Analysis with 0.5 Hz Resolution: Precise analysis of different frequency bands

Normative Databases & Comparison

• Eyes-Open and Eyes-Closed Normative Databases: Full age coverage from 2 months to 82 years (N = 727)
• Dynamic Comparison with Normative Data: Real-time observation of differences from the normative population
• Comparable Parameters: Power, Coherence, Phase Lag, Amplitude Asymmetry, and Power Asymmetry
• One-Click Reference Change: High flexibility in data analysis

3D LORETA Analysis

• sLORETA and swLORETA: Precise calculation of brain wave sources in deep brain regions
• 3D Maps with Talairach Atlas: Accurate display of involved regions
• Functional Network Analysis: Examination of nodes and connections in symptom-related brain networks

Advanced Neurofeedback

• Z-Score Neurofeedback: Online feedback based on comparison with normative database
• LORETA Z-Score Neurofeedback: Deep feedback from specific brain regions
• Surface Z-Score Neurofeedback: Surface feedback with adjustable references
• Cross-Frequency Z-Score Neurofeedback: Analysis and feedback across different frequencies
• BrainSurfer BCI: Brain-computer interface with real-time 3D brain network visualization

Reporting & Documentation

• Automatic Clinical Report Writer (ACR): Automatic generation of clinical reports with treatment protocol suggestions
• Comprehensive Reports: Including charts, brain maps, and statistical analyses
• Export to Various Formats: Transfer data to statistical software

System Requirements

According to official Applied Neuroscience information, the minimum system requirements for running NeuroGuide are as follows:

Note: Using Mac with M1, M2, or M3 chip through Bootcamp is not recommended.

Benefits of Using NeuroGuide 4.0.1

• ✅ Support for over 45 EEG amplifier formats
• ✅ Advanced LORETA capabilities for identifying deep brain sources
• ✅ Accurate Z-Score Neurofeedback based on an extensive normative database
• ✅ Automatic artifact removal without phase distortion
• ✅ Automatic clinical reporting with treatment protocol suggestions
• ✅ Over 200 scientific papers and eight published books based on this software
• ✅ Registered with the FDA (K041263) for clinical use